Journal of Advances in Medicine and Medical Research, ISSN: 2456-8899, ISSN: 2231-0614 (Past),Vol.: 26, Issue.: 7
Coexistence of Sarcoidosis and Tuberculosis Presenting with Severe Pulmonary Artery Hypertension: A Clinical Dilemma
Bhanuja Bhagwat1* and Vijayashree Thyagaraj2 1MS Ramaiah Medical College, Bengaluru, India. 2Department of Internal Medicine, MS Ramaiah Medical College, Bengaluru, India.
Bhanuja Bhagwat1* and Vijayashree Thyagaraj2
1MS Ramaiah Medical College, Bengaluru, India.
2Department of Internal Medicine, MS Ramaiah Medical College, Bengaluru, India.
(1) Babatunde Olanrewaju Motayo, Department of Pathology, Federal Medical Center, Abeokuta, Ogun State, Nigeria and Department of Virology, College of Medicine, University of Ibadan, Ibadan, Nigeria.
(1) Arthur N. Chuemere, University of Port Harcourt, Nigeria.
(2) Godfrey Mutashambara Rwegerera, University of Botswana, Botswana.
(3) Alcibey Alvarado, Clínica de Diagnóstico Médico, Costa Rica.
Complete Peer review History: http://www.sciencedomain.org/review-history/24669
Background: Chronic granulomatous conditions affecting the respiratory system such as tuberculosis and sarcoidosis have similar case presentations suggesting them to be polar ends of the same disease spectrum thus putting physicians into a clinical dilemma. This case report highlights one such unique presentation.
Case Presentation: A young female, presented with respiratory distress and significant weight loss. Investigations showed severe pulmonary artery hypertension (PAH), renal failure and generalized lymphadenopathy suggesting multisystem involvement. The initial diagnosis was sarcoidosis warranting corticosteroids but since Mantoux test suggested tuberculosis we were in a dilemma regarding therapeutic options.
Conclusion: This case highlights a rare presentation of sarcoid tuberculous with severe PAH urging physicians to consider this chronic granulomatous disease spectrum during work up of their patients. The authors would also like to emphasize the importance of starting combined therapy on early recognition to combat a possible disease entity like tuberculous sarcoid patients. These predictors, however, need further work to validate reliability.
Heart blocks; pulmonary artery hypertension; sarcoidosis; sarcoid tuberculous; tuberculosis.
Full Article - PDF Page 1-6
DOI : 10.9734/JAMMR/2018/41337Review History Comments