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Asian Journal of Medicine and Health, 2456-8414,Vol.: 11, Issue.: 1


Outcome of Childhood Tuberculosis at a Specialist Hospital in Gusau, Nigeria


Garba Bilkisu Ilah1*, Muhammad Aminu Sakajiki2, Yusuf Ibrahim3, Ibrahim Tukur Mafara4, Ahmad Murtala Muhammad1, Yusuf Tahir1 and Onazi Sunday Ochapa5

1Department of Paediatrics, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.

2Department of Medicine, Usmanu Danfodiyo University Teaching Hospital, Sokoto, Nigeria.

3Department of Paediatrics, Ahmad Sani Yariman Bakura Specialist Hospital, Gusau, Nigeria.

4Directly Observed Treatment Short course clinic, Ahmad Sani Yariman Bakura Specialist Hospital, Gusau, Zamfara State, Nigeria.

5Department of Paediatrics, Federal Medical Centre, Gusau, Nigeria.

Article Information
(1) Giuseppe Murdaca, Professor, Clinical Immunology Unit, Department of Internal Medicine, University of Genoa, Italy.
(1) V. Bhanu Rekha, Rajiv Gandhi Institute of Veterinary Education and Research, India.
(2) Nitesh Mohan, Rohilkhand Medical College & Hospital, Bareilly International University, India.
Complete Peer review History: http://www.sciencedomain.org/review-history/23625


Introduction: Tuberculosis (TB) is a chronic infectious disease that is preventable and curable, yet a major cause of childhood morbidity and mortality. Tuberculosis prevalence and mortality are under-estimated in many high burden countries. Directly Observed Treatment Short course (DOTS) enhances treatment outcome with an overall reduction in morbidity and development of multidrug resistant TB.

Objective: To determine the pattern and outcome of childhood tuberculosis managed at the DOTS clinic in Gusau, Nigeria.

Methodology: A retrospective study of children managed for TB at the DOTS clinic over a 30 months period. The clinic serves both children and adults. All children (≤ 18years) treated for tuberculosis over the study period were included. Relevant information from the register was retrieved and analysed accordingly. Treatment outcomes were assessed according to World Health Organisation (WHO) and National Tuberculosis and Leprosy Control Programme (NTLCP) guidelines. “Cured’’ and “treatment completed’’ outcomes were classified as treatment successful.

Results: Of the 415 patients managed, 76(18.3%) were children; males were 30(39.5.2%), with a M: F ratio of 1:1.5. Mean±SD age was 8.89±5.38 years, with 29(38.2%) being in the 0-5 years age group. Pulmonary TB (PTB) was seen in 58(76.3%), more females had pulmonary TB than males, which was not significant (χ2=1.350, p=0.245). Seventy-five (98.7) were new cases, with 1(1.3%) treatment after failure.

Acid-fast bacilli (AFB) were positive in 12(15.8%) while GeneXpert MTB/RIF sensitivity was detected in 7(9.2%). Majority 51(67.1%) completed treatment, 12(15.8%) were cured, 9(11.8%) were transferred out, 3(3.9%) died, while 1(1.3%) was lost to follow up; with the successful outcome of 82.9%.

Conclusion: Treatment outcome using DOTS strategy was excellent, with a success rate close to 85.0% of WHO benchmark. The proportion of childhood TB indicates that childhood TB as compared to the adult cases is still under diagnosed and undertreated.

Keywords :

Childhood; DOTS; gusau; tuberculosis; outcome.

Full Article - PDF    Page 1-5

DOI : 10.9734/AJMAH/2018/40490

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