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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 10, Issue.: 11

Case Report

Acute B-Cell Lymphoblastic Leukemia/Acute B-Cell Lymphoblastic Lymphoma Presenting as Bilateral Breast Masses


Burak Ilhan1, Fatma Sen2, Rustu Turkay3 and Hasan Karanlik4*

1Department of General Surgery, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkey.

2Department of Medical Oncology, Institute of Oncology, Istanbul University, Istanbul, Turkey.

3Department of Radiology, Istanbul Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Istanbul, Turkey.

4Surgical Oncology Unit, Institute of Oncology, Istanbul University, Istanbul, Turkey.

Article Information


(1) Alex Xiucheng Fan, Department of Biochemistry and Molecular Biology, University of Florida, USA.


(1) Arda Isik, Erzincan University, Turkey.

(2) Ketan Vagholkar, D. Y. Patil University, India.

Complete Peer review History: http://sciencedomain.org/review-history/11331


Aims: Metastases of leukemia and lymphoma to both breasts were very rare. We have aimed to report a rare and interesting case that presented with metastases of leukemia and lymphoma to both breasts.

Case Report: A thirty-year-old woman has applied to our department with a four month story of painless masses in both of breasts. We have performed tru-cut biopsies to both breasts after clinical examination. Histological and immuno-histochemical profile analysis have revealed bilateral acute B - cell lymphoblastic lymphoma and acute B - cell lymphoblastic leukemia metastases. A positive response was observed after treating the patient with adjuvant systemic chemotherapy and consolidated radiation therapy. On the sixth month follow-up, no evidence of disease recurrence was identified.

Discussion: In patients presenting with bilateral breast masses, considering that other tumors may metastasize to the breast, the details of this rare case may aid clinicians treating similar patients, and highlight the importance of this situation.

Conclusion: This finding emphasizes the need to accurately identify these tumors as metastases in order to avoid unnecessary procedures and treatments in these patients.

Keywords :

Leukemia; lymphoma; breast involvement; metastasis.

Full Article - PDF    Page 1-5

DOI : 10.9734/BJMMR/2015/20637

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