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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 8, Issue.: 6

Commentary

Latent Viruses, Microcompetition, Transcription Factor Deficiency and the Cause of Acute Lymphoblastic Leukemia

 

Hanan Polansky1* and Adrian Javaherian1

1The Center for the Biology of Chronic Disease (CBCD), 616 Corporate Way, Suite 2-3665, Valley Cottage, NY. 10989, USA.

Article Information
Editor(s):
(1) C. Cameron Yin, Department of Hematopathology, UT MD Anderson Cancer Center, Houston, TX, USA.
Reviewers:
(1) Anonymous, Unidad De Investigación , México.
(2) Golam Hafiz, Department of Pediatric Hematology and Oncology, Bangabandhu Sheikh Mujib Medical University Shahbag, Bangladesh.
Complete Peer review History: http://www.sciencedomain.org/review-history/9168

Abstracts

The cause of B-cell Acute Lymphoblastic Leukemia (B-ALL) is unknown. Some studies suggested that the cause might be a deficiency in certain transcription factors due to a genetic deletion. We would like to propose a different event that might cause such deficiency. This event is the presence of certain latent viruses in infected cells. The event and its molecular, cellular and clinical consequences have been described by Hanan Polansky in 2003 in his book on Microcompetition.

Keywords :

Microcompetition; transcription factor deficiency; latent virus; B-cell acute lymphoblastic leukemia; B-all; epstein-barr virus; cytomegalovirus.

Full Article - PDF    Page 541-543 Article Metrics

DOI : 10.9734/BJMMR/2015/18095

Review History    Comments

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