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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 8, Issue.: 10

Review Article

Alternatives to Hormone Replacement Therapy in Postmenopausal Women


M. Najimudeen1*, K. Sachchithanantham1 and B. Sameera1
1Departmen of Obstetrics and Gynaecology, Melaka Manipal Medical College, Malaysia.

Article Information
(1) Yoshihiro Nishida, Department of Obstetrics and Gynecology, Faculty of Medicine, Oita University, Yuhu-city, Japan.
(1) A. Papazafiropoulou, Department of Internal Medicine and Diabetes Center, Tzaneio General Hospital of Piraeus, Greece.
(2) Pietro Scicchitano, Cardiology Department, Hospital “F. Perinei”, Altamura (Bari), Italy.
Complete Peer review History: http://www.sciencedomain.org/review-history/9498


Substantial number of postmenopausal women suffers in silence. They experience vasomotor symptoms, sleep disturbances, atrophic changes in the genital and urinary systems and lack of sexual desire. The fear, side effects and contra indications of oestrogen discourage hormone replacement therapy.
Life style modification with change in dietary habit, regular exercise, cessation of alcohol and smoking can help them immensely. Tibolone, Selective oestrogen receptor modulators (SERMs), Antidepressants like Venlafaxine, th Alpha 2 agonists like clonidine, carbapentine and various supplements are frequently prescribed. Available alternatives and their merits are discussed.

Keywords :

Postmenopause; hormone replacement; lifestyle; tibolone; SERMs.

Full Article - PDF    Page 816-828

DOI : 10.9734/BJMMR/2015/18412

Review History    Comments

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