British Journal of Pharmaceutical Research, ISSN: 2231-2919,Vol.: 6, Issue.: 4
Evaluation of Analgesic Activity and Phytochemical Screening of Clitoria ternatea Linn
Shital S. Chavan1*, Ravindra S. Jadhav2, Deepak Kharat2, Someshwar D. Mankar2 and R. K. Godge2 1Department of Pharmacognosy, University of Mumbai, Government College of Pharmacy, Ratnagiri, Maharashtra, India.
2Department of Pharmacognosy, University of Pune, Pravara Rural College of Pharmacy, Loni, Maharashtra, India.
Shital S. Chavan1*, Ravindra S. Jadhav2, Deepak Kharat2, Someshwar D. Mankar2 and R. K. Godge2
1Department of Pharmacognosy, University of Mumbai, Government College of Pharmacy, Ratnagiri, Maharashtra, India.
(1) Syed A. A. Rizvi, Department of Pharmaceutical Sciences, College of Pharmacy, Nova Southeastern University, USA.
(2) Alyautdin Renad N, The Department of Pharmacology (Pharmaceutical Faculty), I. M. Sechenov MSMU, Moscow, Russia.
(1) Anonymous, India.
(2) P. G. Latha, Ethnomedicine and Ethnopharmacology Division, Jawaharlal Nehru tropical Botanic Garden and Research Institute (JNTBGRI), India.
(3) Halima Sadiya Abdullahi Gero, Pharmacology and Therapeutics, Ahmadu Bello University, Zaria, Nigeria.
Complete Peer review History: http://www.sciencedomain.org/review-history/8505
Clitoria ternatea L. is a member of the family Fabaceae, commonly known as ‘Aparajita’ or Girikarnika. It is a perennial climber widely used in the traditional Ayurvedic system of Indian medicine for treating a wide variety of ailments. Nowadays available drugs for the management of pains, fever, and inflammation like conditions are having many adverse effects; hence there is need for the drugs from other safer sources which will be highly safer having little or no side effects. For this purpose, Clitoria ternatea Linn leaves (Fabaceae) were screened for its phyto and pharmacological especially analgesic properties using hotplate and tail immersion method with mice. The analgesic study of Clitoria ternatea Linn leaves showed that the petroleum ether extract of the leaves have significant activity compared to pentazocin which is used as a standard. Generally Tannins, flavonoids, alkaloids and saponins are responsible for the analgesic and anti-inflammatory activities in many medicinal plants; hence phytoconstituents from plant leaves are also studied. These results may explain the use of the plant for the management of pains and its related ailments in the region where it is commonly found.
Analgesic activity; Clitoria ternatea; hot plate method; tail immersion test.
Full Article - PDF Page 255-260
DOI : 10.9734/BJPR/2015/13593Review History Comments