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European Journal of Medicinal Plants, ISSN: 2231-0894,Vol.: 3, Issue.: 1 (January-March)

Original-research-article

In-vitro Anti-Inflammatory Evaluation of Crude Bombax ceiba Extracts

 

K. Anandarajagopal1*, J. Anbu Jeba Sunilson1, T. V. Ajaykumar2, R. Ananth2 and S. Kamal2

1School of Pharmacy, KPJ Healthcare University College, Kota Seriemas, Nilai 71800, Negeri Sembilan, Malaysia.
2Arulmigu Kalasalingam College of Pharmacy, Krishnankoil 626 190, Tamilnadu, India.

Article Information

Editor(s):

(1) Anonymous.

Reviewers:

(1) Emdad Hossain, Pharmacy College, India.

(2) Anonymous.

(3) Pius Tshimankinda MPIANA, University of Kinshasa, Congo.

Complete Peer review History:http://www.sciencedomain.org/review-history/776

Abstracts

Aims: The present work was decided to evaluate the in-vitro anti-inflammatory activity of crude extracts of Bombax ceiba in order to characterize the role of this extract in affecting the inflammatory process.
Study Design: Extraction of B. ceiba bark, phytochemical screening, and evaluation of in-vitro anti-inflammatory activity.
Methodology: Petroleum ether, ethanol and aqueous extracts of B. ceiba barks were prepared by maceration technique and subjected to preliminary phytochemical tests. The in-vitro anti-inflammatory activity of all extracts (1000 mcg/ml) was assessed by HRBC membrane stabilization method.
Results: Ethanol extract showed significant (p<0.001) response followed by aqueous extract (p<0.01) when compared with standard, diclofenac potassium (50 mcg/ml).
Conclusion: The study suggests that the extracts possess enough potential to reduce inflammation by in-vitro and directs the importance of further research and development of novel anti-inflammatory agents.

Keywords :

In-vitro anti-inflammatory; Bombax ceiba; extracts; HRBC membrane stabilization.

Full Article - PDF    Page 99-104

DOI : 10.9734/EJMP/2013/2113

Review History    Comments

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