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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 6, Issue.: 7


Clinical Profile and Factors Related to Compliance with Benzathine Penicillin G Prophylaxis among RF/RHD Patients at the Tarlac Provincial Hospital, Philippines


Rafael T. Respicio1 and Lolita V. Sicat2*

1Department of Pediatrics, Tarlac Provincial Hospital, San Vicente, Tarlac City, Philippines.
2Research and Evaluation, Tarlac State University, Tarlac City, Philippines.

Article Information
(1) Oswin Grollmuss, Department of Pediatric and Adult Resuscitation Congenital Heart of Centre Chirurgical Marie Lannelongue, University Paris XI , France.
(1) Metin Do─čan, Department of Medical Microbiology, Necmettin Erbakan University, Meram Medical School, Turkey.
(2) Anonymous, USA.
(3) Anonymous, Brazil.
(4) Anonymous, South Africa.
Complete Peer review History: http://www.sciencedomain.org/review-history/7634


Rheumatic fever (RF) and Rheumatic heart disease (RHD), despite a documented decrease in their incidence, remain as problems in both industrialized and industrializing countries even at the beginning of the 21st century. The most devastating effects are on children and young adults in their most productive years.
To determine the clinical profiles of RF/RHD patients at Pediatric Department of Tarlac Provincial Hospital, Tarlac city, Philippines and the factors related to their compliance with Benzathine Penicillin G Prophylaxis treatment, the ex post-facto research was done using the charts of patients. Out patients and ward patients diagnosed with RF/RHD patients were identified using the Jones Criteria. They served as the subjects of the study.
The onset of the RF/RHD was seen in age ranging from 6 years to 17 years old with most of them occurring at 7-15 age range. The male to female ratio was 1.3:1. The RF/RHD patients came from different towns of Tarlac, the most number of which came from the city of Tarlac. The patients, being clientele of a provincial and non- paying hospital, came from poor family with low educational attainment, and low monthly income from skilled or unskilled work. Carditis (55% of the 58 cases) and polyarthritis (43%) were the most frequent manifestations seen among patients. In the minor manifestations of RF, majority had episodes of acute tonsillopharyngitis (82%) and fever (82%). Laboratory results, showed abnormal ESR (55 or 95% of the 58 cases), ASO titers (47 or 81%), PR intervals (18 or 31%), and leukocytosis (30 or 67%). Of the 26 cases who had valvular involvement cases, 7 mitral regurgitation; 2 (7%) had mitral stenosis; and 1 had aortic regurgitation. The rest had combination or triple combinations of valvular involvement. Compliance with Benzathine Penicillin G treatment was 46.6%. Compliance to treatment is related to the occupation of father (x2= 6.643, significant at .0361 level) and family income (x2= 8.088, significant at .0175 levels.
Poor families who have low paying jobs are less likely to complete the treatment of their sick children. The Department of Health must find ways to provide the secondary chemoprophylaxis to RF/RHD patients for free to improve the compliance rate, thus, provide bigger chance for the RF/RHD patients to survive their disease.

Keywords :

Benzathine Penicillin G Prophylaxis; Rheumatic fever (RF) and Rheumatic heart disease (RHD); compliance; Tarlac Provincial Hospital.

Full Article - PDF    Page 699-708

DOI : 10.9734/BJMMR/2015/12084

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