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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 6, Issue.: 4

Short Research Article

In vitro Bacteriostatic Effect of a Scaffold with a Mixture of Hypericum perforatum and Azadirachta indica Oil Extracts


Maria Letizia Iabichella1*

1HELIOS MED ONLUS, International Health Cooperation, Italy.

Article Information
(1) Arun Kumar Nalla, College of Medicine, University of Illinois, Peoria, IL, USA.
(1) Anonymous, Turkey.
(2) Anonymous, Brasil.
Complete Peer review History: http://www.sciencedomain.org/review-history/7489


Background: Clinical evidences suggest antimicrobial activities of a new oil extract mixture of Hypericum perforatum and Azadirachta indica, included in a polymeric scaffold (or Hyperoil™ Polimeric Substrate - HPS).
Methods: Bacteriostatic activity was investigated on selected strains of Staphylococcus aureus (ATCC® 12598™), Pseudomonas aeruginosa (ATCC® 10145™) and Klebsiella ozaenae AM through standardized in vitro tests.
Results and Conclusion: All bacterial strains were stabilized or reduced in size after 3 and 24 hours contact with the HPS if compared to the empty polymeric scaffolds.
Results showed the bacteriostatic effect of HPS that, added with its anti-inflammatory properties, could explain its tissue repair effects observed in vivo.

Keywords :

Hypericum perforatum; Azadirachta indica; Staphylococcus aureus (ATCC® 12598™); Klebsiella ozaenae AM and Pseudomonas aeruginosa (ATCC® 10145™); bacteriostatic effect; scaffold; Hyperoil™ polymeric substrate.

Full Article - PDF    Page 431-438

DOI : 10.9734/BJMMR/2015/14258

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