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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 4, Issue.: 36 (21-31 December)

Review Article

Hepatitis C Virus Infection and Coronary Arteriosclerosis: The Growing Evidences


Hesham Ibrahim Elmakhzangy1* and Reem Hamdy A. Mohammed2

1Department of Tropical Medicine, School of Medicine, Cairo University, Egypt.
2Department of Rheumatology, School of Medicine, Cairo University Hospitals, Egypt.

Article Information


(1) Dr. Fuhong Su, ICU Laboratory, Erasme Hospital, Free University Brussels, Brussels, Belgium.


(1) Julieta Trinks, Institute of Basic Sciences and Experimental Medicine, Hospital Italiano de Buenos Aires, Argentina.

(2) Shalini Malhotra, Microbiology department, Delhi University, India.

Complete Peer review History: http://www.sciencedomain.org/review-history/5814


Arteriosclerosis is a chronic inflammatory vascular pathology that features a leading cause of coronary artery disease contributing to significant mortality and reduced quality of life. The recent identification of the possible role of infections in the initiation of a serious of inflammatory events represents an interesting development towards the better understanding of immune mediated vascular injury and premature atherosclerosis in patients with chronic HCV infection. A number of factors related to chronic HCV infection have been hypothesized to contribute to arteriosclerosis. The current review displays some of the aspects of interaction between the chronic viral infection, the immune system and cytokine networks and its relation to the increased risk of coronary artery disease.

Keywords :

Coronary arteriosclerosis; chronic hepatitis C virus infection; pro-inflammatory cytokines; metabolic syndromes; dyslipidemia.

Full Article - PDF    Page 5715-5728

DOI : 10.9734/BJMMR/2014/12747

Review History    Comments

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