British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 4, Issue.: 34 (01-10 December)
Body Mass Index and Blood Pressure Pattern through Menarcheal Age in an Italian Village
Vincenzo Maggisano1, Flavia Chiarotti2, Anna Livia Loizzo3 and Alberto Loizzo4* 1Department of Nephrology and Dialysis, San Giuseppe Hospital, ASL RM H, 00041 Albano Laziale, Italy.
2Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, via Regina Elena 299, 00161 Roma, Italy.
3Didasco Centre for Sick Children, National Health Service ASL RM B, via Pescosolido 160, 00158 Roma, Italy.
4Department of Therapeutic Research and Medicines Evaluation, Istituto Superiore di Sanità, via Regina Elena 299, 00161 Roma, Italy.
Vincenzo Maggisano1, Flavia Chiarotti2, Anna Livia Loizzo3 and Alberto Loizzo4*
1Department of Nephrology and Dialysis, San Giuseppe Hospital, ASL RM H, 00041 Albano Laziale, Italy.
(1) Mohamed Essa, Department of Food Science and Nutrition, Sultan Qaboos University, Oman.
(2) Salomone Di Saverio, Emergency Surgery Unit, Department of General and Transplant Surgery, S. Orsola Malpighi University Hospital, Bologna, Italy.
(1) Konstantina Dipla, Aristotle University of Thessaloniki, Greece.
Complete Peer review History: http://www.sciencedomain.org/review-history/5488
Aims: Recent investigations correlated early menarche to cardiovascular risk factors in adulthood, whereas others underlined relationship of menarcheal age to body mass index (BMI) and dysmetabolic conditions. Our aim was to assess whether early menarche could indicate an increased risk factor for enhanced blood pressure and/or hypertensive-range values (systolic/diastolic blood pressure beyond the 95th percentile) within the narrow window of the sexual maturation, 12y to 14y.
Methodology: 463 Caucasian Italian girls were studied at both 12y and 14y: body height (BH), weight (BW), BMI, systolic-diastolic blood pressure (SBP, DBP), presence-absence of menarche were recorded.
Results and Discussion: Lowest quartile for BH, BW, BMI in 12y girls was associated with lower probability (~-20%) of having menarche before 14y. Conversely, girls who developed menarche before 12y, at 12y showed higher average BH, BW, BMI, SBP/DBP values versus girls who developed menarche after 12y (about +3.2%;+16.2%;+8.8%;+5.5%;+9.2%, respectively). However, 14y girls of all groups showed similar average SBP and DBP and similar prevalence for hypertensive-range values. Interestingly, at 12y BMI was correlated to hypertensive values of both 12y and 14y (X2=17.5; X2=15.9; respectively; P<.001). Regression analysis showed that unitary increase of BMI at 12y yielded an increase of 1.04 mmHg for SBP and 0.55 mmHg for DBP in 14y girls.
Conclusions: Early menarcheal age (before 12y) was accompanied by higher SBP and DBP at 12y, but also by higher BH, BW and BMI, versus girls with menarche after 12y. However, early menarcheal age did not influence average SBP/DBP and prevalence of hypertensive-range values in 14y girls. BMI was strongly related to menarcheal status at both 12y and 14y, thus indicating that within this age (12y to 14y) BMI influenced both menarcheal triggering and blood pressure. Further investigations are needed to verify whether cardiovascular risk factors are influenced also in adult age by early menarche, or by high BMI at 12y-14y.
Body mass index, body height, body weight, hypertensive values, pubertal age.
Full Article - PDF Page 5385-5397
DOI : 10.9734/BJMMR/2014/7006Review History Comments