Quick Menu

Upcoming Journals

British Journal of Medicine and Medical Research

British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 2, Issue.: 3 (July-September)

 

Review Article

 

Mucosal Vaccination against Enteric Pathogens in the Developing World
 

 

William Langridge1*, Oludare Odumosu1, Somen Nandi3, Raymond Rodriguez3, Marino DeLeon1 and Zaida Cordero-MacIntyre2
1Department of Biochemistry and Center for Health Disparities and Molecular Medicine, Loma Linda School of Medicine, Loma Linda University, Loma Linda CA. 92354.
2School of Public Health, Loma Linda University, Loma Linda CA, 92354.
3Global HealthShare, Department of Molecular & Cellular Biology, College of Biological Sciences, University of California, Davis, Davis, CA 95616.

 

Abstracts

 

Of the approximately 9 million children under the age of 5 yr that die annually in developing nations, about 5.1 million will die from preventable infectious diseases. This disastrous human and economic loss is caused in large part by three types of acute diarrhea and attendant respiratory tract infections that are responsible for approximately 2.6 million of these deaths. Thus, enteric pathogens remain a major factor contributing to persistent poverty and poor health in developing nations. Novel mucosal vaccination strategies are emerging that can protect epithelial surfaces and therefore promise a simple, effective and safe interventional therapy to overcome the mortality generated by these debilitating infectious diseases. Before the full potential for mucosal vaccination against enteric diseases can be realized, the innate immune system must be strengthen by addressing secondary problems such as malnutrition, malabsorption and gastrointestinal tract impairment.
Here we describe the major enteric pathogens responsible for childhood morbidity and mortality in developing and resource-limited countries. We also discuss the development of mucosal vaccination strategies that when combined with modern principles of nutritional therapy may help improve the health and socio-economic status of developing nations.

 

Keywords :

Poverty, malnutrition; immunostimulation; enteric disease; parasites; rotavirus mucosal vaccines; health disparities.

 

Full Article - PDF    Page 260-291    Article Metrics

 

DOI : 10.9734/BJMMR/2012/882

Review History    Comments

Search this site

Advanced Search

Announcement & News

Journal Repository (JR): Permanent Digital Archiving of SDI journals

SDI is happy to announce that all our journals are now permanently archived in Journal Repository (J...

Index Copernicus Value of British Journal of Medicine and Medical Research

  We are delighted to inform that Index Copernicus (a leading indexing organization ...

SDI journal got 35th ranking in Publons

We are delighted to announce (as of 04/01/2016) that British Journal of Medicine and Medical Re...

Growth of SDI and world publication market

As of 2014, total 25,064 journals are competing in World market of journal publication. In 2011, tot...

Publication and site statistics (up to Sept, 2015)

  Number of submission: 22181 (Total up to Sept, 2015) Number of published paper: 10949&n...

Index Medicus selected 15 SDI journals

We are delighted to inform that Index Medicus (IMSEAR) has selected following 15 SDI journals for in...

SCIENCEDOMAIN international received 5844 submissions in 2013

SCIENCEDOMAIN international is pleased to announce that it has received 5844 submissions in 2013, ac...

Science (IF: 31) report confirmed the high standard of SDI journal

As per a recent report (Link) of Science journal (present Impact factor 31), one of our journal (Bri...

Polish Ministry of Science and Higher Education included 18 SDI journals in its official report of 2013

SDI is pleased to announce that Polish Ministry of Science and Higher Education included 18 SDI jour...

SDI introduced Post-publication peer review by its comment section

SDI journals encourage Post-publication peer review by its comment section   Policy details a...



SCIENCEDOMAIN Awards

Browser Compatibility : Mozila firefox, Google Crome and IE 7 & above. Creative Commons License Terms & Condition   |   Privacy Policy   |   Join Us   |   Help   |   Contact Us
© Copyright 2010-2017, SCIENCEDOMAIN international. All rights reserved.