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British Biotechnology Journal, ISSN: 2231-2927,Vol.: 4, Issue.: 4 (April)

Original-research-article

Antibacterial Activities of Six Medicinal Plants Used Traditionally by Saudi People to Treat Common Diseases

 

Hameda El Sayed Ahmed El Sayed1* and Magda M. Aly2,3

1Departement of Biology, Faculty of Applied Science, Umm Al Qura University, Makkah Al Mukaramah, Kingdom of Saudi Arabia, Saudi Arabia.
2Department of Biology, Faculty of Science, King Abdulaziz University, PO Box 80203, Jeddah 21589, Saudi Arabia.
3Department of Botany, Faculty of Science, Kafrelsheikh University, Egypt.

Article Information

Editor(s):

(1) Yan Juan, Doctorate of Horticultural Crop Biotechnology Breeding, Sichuan Agricultural University, Ya’an, China.

(2) Mayur Kumar Kajla, University of Wisconsin-Madison, Madison, USA.

(3) Chung-Jen Chiang, Department of medical laboratory Science and Biotechnology, China Medical University, Taiwan.

(4) Kuo-Kau Lee, Department of Aquaculture, National Taiwan Ocean University, Taiwan.

Reviewers:

(1) Anonymous.

(2) Adesiji Yemisi Olukemi, Ladoke Akintola University of Technology, Nigeria.

Complete Peer review History: http://www.sciencedomain.org/review-history/4216

Abstracts

Antibiotic resistance is increasing and dangerous problem resulting in a decrease in the used number and fully active antimicrobial agents available to treat infections with multi-drug resistant (MDR) bacteria. Herbal medicines may be an alternative treatment options. This study aimed to evaluate the antibacterial activities of some medicinal plants used traditionally in Saudi Arabia against some pathogenic and MDR bacteria. The antimicrobial activities of water and organic crude extracts were prepared. Out of the 6 plants tested, 5 showed antimicrobial activities against one or more of the tested genera using paper disc diffusion assay. The most active antimicrobial plants were the extract of Azadirachta indica (neem), Zingiber officinale (ginger) Eucalptus globules, Rosmarinus officinalis and Lawsonia inermis with minimal inhibitory concentration (MICs) values ranged from 50-150µg/ml. Lepidium sativium have very weak activity with MIC of ≥200 µg/ml. At 600µg/ml, no toxicity was recorded for all tested extracts except of A. indica extract that showed toxicity (% of mortality ≥50). No antitumor activities for the different plant extracts were recorded against Human gastric cancer SGC-7901 cells. The biological activities may be due to some photochemical compounds including Anthocyanin, Butacyanin, Phytobutanins, Flavonoides, Stetoides and/or Saponins.

Keywords :

Antimicrobial activity; plant extract; azadirachta; eucalyptus; zingiber; rosmarinus; escherichia; lepidium.

Full Article - PDF    Page 499-510

DOI : 10.9734/BBJ/2014/8532

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