Quick Menu

Upcoming Journals

British Journal of Medicine and Medical Research

British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 4, Issue.: 16 (01-10 June)

 

Original Research Article

 

Fertility Enhancing Potential of Mucuna pruriens Seeds in Female Sprague-Dawley Rats

 

 

Ojo Temitope Noah1, Gbotolorun Stella Chinwe1* and Oremosu Ademola Ayodele1

1Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Nigeria.

 

Abstracts

 

Aims: To determine the effect of oral administration of methanolic seed extract of Mucuna pruriens (M. pruriens) on oestrous cycle, ovulation, reproductive hormones and oxidative stress in the ovary of cyclic Sprague-Dawley rats.
Design: Prospective animal study related to M. pruriens in reproductive area.
Place and Duration: Animal Facility of the Department of Anatomy, Faculty of Basic Medical Sciences, College of Medicine of the University of Lagos, Nigeria between the months of June 2012 and August, 2012.
Methodology: Forty female Sprague-Dawley rats with regular 4 days cycle averagely weighing 145 g were used. Methanolic extract of M. pruriens was given orally at 50, 100 and 200 mg/kg body weight. Oestrous cycle was monitored daily. At the end of the experiment animals were sacrificed by cervical dislocation. Oocytes were counted, blood and ovaries were assayed for hormonal and biochemical studies respectively.
Results: Oestrous cycle remained unchanged in the treatment groups. Catalase and superoxide dismutase levels were increased slightly compared to control. A dose dependent increase in FSH and LH (p < 0.05 at 200 mg/kg) levels were observed with an increase in the number of oocytes released at ovulation compared to control.
Conclusion: M. pruriens seed extract has the potential to enhance fertility by increasing serum levels of FSH and LH which in turn increases the number of oocytes released at ovulation possibly through its antioxidant properties.

 

Keywords :

Mucuna pruriens; ovulation; oxidative stress markers; FSH; LH.

 

Full Article - PDF    Page 3148-3157    Article Metrics

 

DOI : 10.9734/BJMMR/2014/8070

Review History    Comments

Search this site

Advanced Search

Announcement & News

Journal Repository (JR): Permanent Digital Archiving of SDI journals

SDI is happy to announce that all our journals are now permanently archived in Journal Repository (J...

Index Copernicus Value of British Journal of Medicine and Medical Research

  We are delighted to inform that Index Copernicus (a leading indexing organization ...

SDI journal got 35th ranking in Publons

We are delighted to announce (as of 04/01/2016) that British Journal of Medicine and Medical Re...

Growth of SDI and world publication market

As of 2014, total 25,064 journals are competing in World market of journal publication. In 2011, tot...

Publication and site statistics (up to Sept, 2015)

  Number of submission: 22181 (Total up to Sept, 2015) Number of published paper: 10949&n...

Index Medicus selected 15 SDI journals

We are delighted to inform that Index Medicus (IMSEAR) has selected following 15 SDI journals for in...

SCIENCEDOMAIN international received 5844 submissions in 2013

SCIENCEDOMAIN international is pleased to announce that it has received 5844 submissions in 2013, ac...

Science (IF: 31) report confirmed the high standard of SDI journal

As per a recent report (Link) of Science journal (present Impact factor 31), one of our journal (Bri...

Polish Ministry of Science and Higher Education included 18 SDI journals in its official report of 2013

SDI is pleased to announce that Polish Ministry of Science and Higher Education included 18 SDI jour...

SDI introduced Post-publication peer review by its comment section

SDI journals encourage Post-publication peer review by its comment section   Policy details a...



SCIENCEDOMAIN Awards

Browser Compatibility : Mozila firefox, Google Crome and IE 7 & above. Creative Commons License Terms & Condition   |   Privacy Policy   |   Join Us   |   Help   |   Contact Us
© Copyright 2010-2017, SCIENCEDOMAIN international. All rights reserved.