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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 4, Issue.: 15 (21-31 May)

Case Study

Guillain Barre Syndrome: A Rare Presentation Mimicking Acute Stroke


Naeem Abbas1*, Saddam Aldabag2, Ghulam Akbar2, Mohammad Hossain2, Hasan Al-Azzawi2, Gretchen Boling2 and Abdalla Yousif2

1Department of Internal Medicine, Bronx Lebanon Medical Center, Bronx, New York, USA.
2Department of Internal Medicine, Raritan Bay Medical Center, Perth Amboy, New Jersey, USA.

Article Information


(1) Umit Bagriacik, Department of Immunology, Gazi University, Turkey.


(1) Anonymous.

(2) Hugo Juarez Olguin, Universidad Nacional Autónoma de México, México.

Complete Peer review History: http://www.sciencedomain.org/review-history/3942


Guillain Barre Syndrome (GBS) is an acute neuromuscular weakness and paralysis associated with areflexia and often spontaneous recovery, but carries the potential risk of respiratory depression owing to muscle weakness. Worldwide, 1 to 3 cases/100,000 are reported. The syndrome is most commonly reported as symmetrical ascending weakness in arms and legs accompanied by hyporeflexia or areflexia. Sensory disturbances are not required for diagnosis, but may or may not be present. Acute inflammatory demyelinating poly-radiculoneuropathy (AIDP) is the most common variant, but acute motor and sensory axonal neuropathy (ASMAN) is more severe and usually leads to partial or slow recovery. We present a case of GBS presenting with asymmetric weakness and sensory disturbance in a patient with bloody diarrhea of unknown etiology. This patient had asymmetrical paralysis mimicking stroke, but the physical findings, laboratory studies, normal CT and MRI of the brain, Electromyogram (EMG) and the patient’s improvement with Intravenous Immunoglobulin (IVIG) support the diagnosis of GBS. People with inflammatory bowel disease are at increased risk of developing GBS. Persons with antecedent Campylobacter jejuni infections are 77 percent more likely to contract GBS compared to the general population, and Cytomegalovirus (CMV) and Epstein Barr virus (EBV) are also implicated risk factors.

Keywords :

Guillain-barre syndrome; acute inflammatory demyelinating poly-radiculoneuropathy (AIDP); acute motor and sensory axonal neuropathy (ASMAN); amyotrophic lateral sclerosis; mono-neuritis multiplex; campylobacter jejuni.

Full Article - PDF    Page 3009-3015

DOI : 10.9734/BJMMR/2014/7226

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