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Journal of Advances in Medicine and Medical Research, ISSN: 2456-8899, ISSN: 2231-0614 (Past),Vol.: 26, Issue.: 11

Opinion Article

QT Interval Variability in Patients with Obstructive Sleep Apnea


Mohammad Hashemi Jazi1, Babak Amra2, Khadijeh Miadi1*, Mansour Jahangiri3, Ali Gholamrezaei4, Faezeh Tabesh1 and Mohammad Reza Yazdchi5

1Department of Cardiology, Isfahan University of Medical Sciences, Isfahan, Iran.

2Department of Internal Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

3Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran.

4Department of Chronic Diseases, Translational Research Center for Gastrointestinal Disorders, Metabolism and Ageing, University of Leuven, Leuven, Belgium.

5Department of Biomedical Engineering, Isfahan University of Medical Sciences, Isfahan, Iran.

Article Information


(1) Pietro Scicchitano, Cardiology Department, Hospital “F. Perinei” Altamura (Ba), Italy.


(1) Eva Libman, McGill University, Canada.

(2) Gaurav Nigam, Clay County Hospital, USA.

Complete Peer review History:


Aims: Obstructive sleep apnea (OSA) increases the risk of cardiac arrhythmias. We investigated QT interval variability among OSA patients.

Study Design: It is a descriptive-cross-sectional study.

Methodology: Newly diagnosed OSA patients and healthy controls were studied. Inter-heartbeat and QT intervals were extracted from electrocardiography (for 1 hour at 3 AM). QT interval metrics including duration and variability indexes were compared between patients and controls.

Results: 35 patients and 13 controls were studied. There was no difference between patients and controls, neither between mild/moderate OSA versus severe OSA patients, in the measured QT interval variables. No significant correlation was found between apnea severity and the measured QT interval variables.

Conclusion: We found no difference between OSA patients and controls in QT variability. Also, no clear association between OSA severity and QT variability was observed.

Keywords :

Sleep apnea; arrhythmia; cardiovascular; cardiac electrophysiology.

Full Article - PDF    Page 1-5

DOI : 10.9734/JAMMR/2018/41277

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