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British Journal of Medicine and Medical Research

British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 4, Issue.: 5 (11-20 February)

Opinion Article

Recognizing Paradigm Instability in Theories of Carcinogenesis

 

Stuart G. Baker1*

1Division of Cancer Prevention, National Cancer Institute, Bethesda, MD 20892, USA.

 

Abstracts

 

The dominant view that cancer arises from successive mutations in somatic cells is so unquestioned that accumulating challenges from experimental and observational results are rarely addressed in the scientific literature. Based on these challenges, we argue that the scientific understanding of carcinogenesis has entered a period of paradigm instability. New research directions are therefore needed.

 

Keywords :

Cancer; funding; paradigm instability; paradox; research; somatic mutation theory; tissue organization field theory.

 

Full Article - PDF    Page 1149-1163    Article Metrics

 

DOI : 10.9734/BJMMR/2014/6855

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