Quick Menu

Upcoming Journals

Asian Journal of Medicine and Health

Asian Journal of Medicine and Health, 2456-8414,Vol.: 11, Issue.: 2

 

Original-research-article

 

Cortisol and Metabolic Syndrome Components in Obese and Overweight Young Adults of a Nigerian Private University

 

 

Adediji, Isaac Oluwole1*, Taiwo Timilehin Darasimi1, Adepoju Paul Olusegun2, Adelakun Ayodele Ademola3, Akinleye Waheed Akindele1 and Afolabi Joy Oluwaseyifunmi   

1Clinical Chemistry Unit, Department of Medical Laboratory Science, Babcock University, Ilishan Remo, Ogun State, Nigeria.

2Histopathology Unit, Department of Medical Laboratory Science, Babcock University, Ilishan Remo, Ogun State, Nigeria.

3Department of Chemical Pathology, Ladoke Akintola University of Technology Teaching Hospital, Ogbomoso, Oyo State, Nigeria.

 

Abstracts

 

Background: Metabolic syndrome is a cluster of metabolic abnormalities which confers upon an individual a substantial increase in cardiovascular disease risk – approximately twice as high as those without the syndrome.

Aim: The study assessed the relationship between serum cortisol and the components of metabolic syndrome among overweight and obese students.

Materials and Methods: A total of ninety (n=90) subjects were recruited for this study which consisted of thirty (30) obese participants, thirty (30) overweight individuals and thirty (30) normal weight individuals who served as controls. About 7 ml of venous blood sample was collected from each participant within the age range of 17-25 years and serum was extracted. Anthropometric measurements were determined using standard methods. Fasting blood glucose, HDL-cholesterol, triglycerides and total cholesterol were determined using enzymatic methods while serum cortisol was determined using enzyme-linked immunosorbent assay (ELISA) technique. Data obtained were statistically analyzed using ANOVA, Post-hoc, Pearson’s correlation and P<0.05 was considered significant. In this study, metabolic syndrome was defined according to the National Cholesterol Education Program (NCEP) criteria.

Results: There was a significant increase in the level of serum cortisol in overweight and obese subjects in comparison to the control participants. There was also positive significant correlation between cortisol and glucose, cortisol and triglyceride. In contrast, there was a negative correlation between cortisol and HDL cholesterol in both overweight (r=-0.917, P=0.02) and obese (r=-0.365, P=0.04) subjects.

Conclusion: This study revealed that increased serum cortisol level in obese and overweight subjects correlates with more than two components of the metabolic syndrome. Taken together, data from this study revealed a noteworthy relationship between cortisol and metabolic syndrome among Nigerian young adults which suggests that metabolic stress is an underlying factor for elevated cortisol.

 

Keywords :

Metabolic syndrome; cortisol; obese; overweight; young adults.

 

Full Article - PDF    Page 1-7    Article Metrics

 

DOI : 10.9734/AJMAH/2018/40623

Review History    Comments

Search this site

Advanced Search

Announcement & News

ISI Thomson Reuters selected British Journal of Pharmaceutical Research for Emerging Sources Citation Index

We are delighted to inform that ISI Thomson Reuters selected British Journal of Pharmaceutical Resea...

SCOPUS selected Annual Research & Review in Biology (ARRB)

We are delighted to inform that famous indexing organization SCOPUS (from Elsevier) selected  A...

Index Copernicus Evaluation Result Released

We are delighted to inform that Index Copernicus (a leading indexing organization from Pol...

Journal Repository (JR): Permanent Digital Archiving of SDI journals

SDI is happy to announce that all our journals are now permanently archived in Journal Repository (J...

SDI journal got 35th ranking in Publons

We are delighted to announce (as of 04/01/2016) that British Journal of Medicine and Medical Re...

Growth of SDI and world publication market

As of 2014, total 25,064 journals are competing in World market of journal publication. In 2011, tot...

Science (IF: 31) report confirmed the high standard of SDI journal

As per a recent report (Link) of Science journal (present Impact factor 31), one of our journal (Bri...

SDI introduced Post-publication peer review by its comment section

SDI journals encourage Post-publication peer review by its comment section   Policy details a...

SDI promotes transparent Advanced OPEN peer review

We have migrated to transparent and toughest ‘Advanced OPEN peer review’ system (...



SCIENCEDOMAIN Awards

  • No Awards listed.

Browser Compatibility : Mozila firefox, Google Crome and IE 7 & above. Creative Commons License Terms & Condition   |   Privacy Policy   |   Join Us   |   Help   |   Contact Us
© Copyright 2010-2018, SCIENCEDOMAIN international. All rights reserved.