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Asian Journal of Biology, 2456-7124,Vol.: 5, Issue.: 3

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Potential Strategies in Treating Tumours

 

Venkata Narasimha Kadali1*, Joyeeta Mitra2, Sheji Chandran1, Teena Sajan2 and Smitha Murthy3#

1Department of Molecular Biology, Avrio Genomics, Bengaluru, Karnataka 560043, India.

2Department of Molecular Biology, Credora Life Sciences, Bengaluru, Karnataka 560043, India.

3Avrio Genomics and Credora Life Sciences, Bengaluru, Karnataka 560043, India.

Article Information

Editor(s):

(1) Vanessa da Silva Carrara, Department of Pharmacy, State University of  Maringa, Brazil.

Reviewers:

(1) Nishitha Thumallapally, Staten Island University Hospital, USA.

(2) Alessandro Poggi, Integrated Oncological Therapies, Policlinico San Martino, Molecular Oncology and Angiogenesis Unit, Italy.

(3) Philippe Groux, Switzerland.

(4) Daisy Machado, UNICAMP, Brazil.

Complete Peer review History: http://www.sciencedomain.org/review-history/23967

Abstracts

Cancer, an absolute sickness exemplified merely by uncontrolled cell proliferation, has always been a concern for universal well-being. The recurrence of cancer is, in fact, mounting globally and fatality rate resulting from this malady is markedly high. Besides genetic alterations, epigenetic modifications also play a vital role in Cancer advancement. Advancements in genomics and proteomics studies enabled researchers to search potential drug targets leading to molecular therapeutics, for instance, Atezolizumab, Nivolumab, Pembrolizumab. This article discusses the potential role of some approaches in treating tumours such as free Hyaluronidase, Hsp90 Inhibitors, Liposomes, Anti–Angiogenesis agents, Apoptosis Proteins Inhibitors, Histone deacetylases inhibitors, Nanomedicine, Blockade of PD‑1/PD‑L1 pathway.

Keywords :

Cancer; proliferation; molecular therapeutics; anti-cancer drug.

Full Article - PDF    Page 1-11

DOI : 10.9734/AJOB/2018/39869

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