International Journal of Biochemistry Research & Review, ISSN: 2231-086X,Vol.: 20, Issue.: 4
Evaluation of High Levels of Triglycerides in Non-alcoholic Fatty Liver Disease
D. Santha Rao1*, V. Praveena1 and Bhukya Veeranna1 1ESIC Medical College, Sanathnagar, Hyderabad, India.
D. Santha Rao1*, V. Praveena1 and Bhukya Veeranna1
1ESIC Medical College, Sanathnagar, Hyderabad, India.
(1) Enrico Sanjust, Associate Professor, Department of Internal Medical Sciences, University of Cagliari, Italy.
(1) Dhastagir Sheriff, Benghazi University, Libya.
(2) Elvira Bormusov, Technion Institute of Technology, Israel.
Complete Peer review History: http://www.sciencedomain.org/review-history/23151
Non-alcoholic fatty liver disease (NAFLD) is starting as accumulation of fat in the hepatocytes (steatosis) which is a sub-clinical condition in those who are not consuming alcohol. Non-alcoholic steatohepatitis (NASH) is a condition of steatosis, associated with inflammation of liver cell. This is a clinical form of NAFLD, which is regarded as a major cause of cirrhosis of the liver . This distinction between simple steatosis and NASH is important because the natural history of these categories differs substantially. Patients with simple steatosis usually have a benign prognosis from the point of view of liver disease [2-5]. In contrast, up to 20% of patients with NASH may ultimately develop advanced liver disease [2,4-6]. The prognosis of NASH-related cirrhosis is poor: It results in liver failure or liver-related death in approximately one third of cases [7,8]. Hepatocellular cancer is also a recently recognized complication of NASH-related cirrhosis [7,9].
Non- alcoholic fatty liver disease(NAFLD); Non alcoholic steatohepatitis(NASH); cirrhosis; liver failure; Hepatocellular cancer; advanced liver disease.
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