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Journal of Applied Life Sciences International, 2394-1103,Vol.: 16, Issue.: 2

Original-research-article

Evaluation of Empirical Functions and Fate of Isomaltose

 

Toluwase Hezekiah Fatoki1*, David Morakinyo Sanni1, Daniel Uwaremhevho Momodu2, Harriet Unuagbon Ugboko3, Catherine Joke Adeseko1 and Bolanle Christianah Faleye4

1Department of Biochemistry, Federal University of Technology, PMB 704, Akure, Ondo State, Nigeria.

2Department of Industrial Chemistry, Federal University Oye, PMB 373, Oye, Ekiti State, Nigeria.

3Department of Biological Sciences, Covenant University, PMB 1023, Ota, Ogun State, Nigeria.

4Department of Chemical Science, Joseph Ayo Babalola University, Ikeji-Arakeji, PMB 5006, Ilesa, Osun State, Nigeria.

Article Information

Editor(s):

(1) Palanisamy Arulselvan, Institute of Bioscience, Universiti Putra Malaysia, Malaysia.

Reviewers:

(1) César Luiz Da Silva Guimarães, Interamerican University of Rondônia, Brazilian Institute of Enviroment and of Natural Renewable Resources, Brazil.

(2) Keagile Bati, University of Botswana, Botswana.

(3) Nelson Pérez Guerra, University of Vigo, Spain.

(4) Oguz Ozcelik, Firat University, Turkey.

Complete Peer review History: http://www.sciencedomain.org/review-history/23105

Abstracts

Aim: To validate the empirical functions of isomaltose and proposed its fates in metabolism using computational analysis.

Place and Duration of Study: This work was carried out at the Department of Biochemistry at the Federal University of Technology Akure Nigeria in 2017.

Methodology: We make use of text mining of experimental articles on isomaltose, predicted the potential targets using Swisstargetprediction server, and the Swisssimilarity server was used for drug similarity analysis.

Results: Isomaltose exhibits antimicrobial activity, biodegradability, non-toxic, and find its use in food, biochemistry and pharmaceutical industries as a prebiotic molecule, precursor metabolite and potent medicine respectively. Isomaltose possibly has a lower glycemic index, with the fate that implicated the production of diglucosamine, by the help of specific aminotransferase, and that there is a possibility of biosynthesis of secondary metabolites through isomaltose pathway.

Conclusion: This study provides the future areas of research and application of isomaltose.

Keywords :

Isomaltose; diglucosamine; novel pathway; in silico; functions; fate.

Full Article - PDF    Page 1-10

DOI : 10.9734/JALSI/2018/39370

Review History    Comments

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