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Asian Journal of Medical Principles and Clinical Practice, XXXX,Vol.: 1, Issue.: 1

Short Research Article

A Primordial Killer Still on the Prowl: A Short Report on Paediatric Tetanus in North-Eastern Nigeria


Iragbogie Al-Mustapha Imoudu1*, Hayatu Ahmad1, Maimuna O. Yusuf1, Hauwa U. Makarfi1 and Tijjani Umara1

1Department of Paediatrics, Federal Medical Centre, Azare, Bauchi State, Nigeria.

Article Information
(1) Fnu Nutan, Assistant Professor, Department of Internal Medicine, Division of Hospital Medicine, Virginia Commonwealth University School of Medicine, Virginia, USA.
(1) Simon Pius, University of Maiduguri Teaching Hospital, Nigeria.
(2) Giuseppe Gregori, Italy.
Complete Peer review History: http://www.sciencedomain.org/review-history/22930


Aims: To examine the clinical profiles and outcomes of neonatal and post-neonatal tetanus as seen at the Federal Medical Centre Azare, North-Eastern Nigeria.

Study Design:  The study was cross-sectional retrospective.

Place and Duration of Study: Department of Paediatrics, Federal Medical Centre, Azare, Nigeria from 1st January to 31st December 2013.

Methodology: Hospital records of patients managed for neonatal and post-neonatal tetanus during the study period were retrieved and analysed. Information obtained included, history, physical examination findings, complications and outcome. SPSS version 17.0 was used for data analysis.

Results: A total of 19 cases were admitted during this period, 6 (31.6%) had neonatal tetanus, while 13 (68.4%) had post-neonatal tetanus. The male: female ratio for neonatal tetanus was 1:1, that of post-neonatal tetanus was 1.6:1. The case fatality rate of neonatal tetanus was 50% and 61.5% for post-neonatal tetanus. The mean age of the neonates who survived the disease differed significantly from that of those who did not survive the disease (P=.03). This was also true for incubation period (P= .01). Mean incubation period and onset time for post-neonatal tetanus was longer in survivors than non-survivors. However, these differences did not reach statistical significance (P= .59, .50 respectively). The portal of entry of post neonatal tetanus had a statistically significant relationship with the outcome (P= .02).

Conclusion: Mortality from tetanus remains high, the importance of preventive strategies in its management cannot be overemphasized in our environment.

Keywords :

Primordial killer; clinical profile; outcome; neonatal tetanus; post-neonatal tetanus; Azare.

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