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Journal of Advances in Medical and Pharmaceutical Sciences, 2394-1111,Vol.: 15, Issue.: 3


Routine Histopathological Analysis of Non-suspicious Looking Foreskin for Adult Patients: Is It Necessary?


N. Kadi1*, L. Kayali2 and A. S. Bates3

1Leighton Hospital, Mid Cheshire, United Kingdom.

2Nottingham University Hospitals, Nottinghamshire, United Kingdom.

3University Hospitals of Leicester, Leicestershire, United Kingdom.

Article Information


(1) Hamdy A. Sliem, Professor, Internal Medicine, Suez Canal University, Egypt and College of Dentistry, Qassim University and EL-Jouf University, Saudi Arabia.


(1) Guven Aslan, Dokuz Eylul University, Turkey.

(2) Alok Nahata, Malaysia.

(3) Diana C. Tapia-Pancardo, National Autonomous University of México, México.

Complete Peer review History: http://www.sciencedomain.org/review-history/22246


Objective: To evaluate the routine histopathological analysis of foreskin in adult patients and determine whether histological processing is necessary in patients with non-suspicious foreskin. 

Materials and Methods: All adult foreskin sent for histopathological analysis between September 2014 and February 2016 at a single institution (Leighton hospital) was included in this study. Histology was compared to macroscopic appearances. A cost analysis was performed.

Results: There were 262 specimens of foreskin sent for histopathological analysis between September 2014 and February 2016. The average age for patients was 48.5 years. Most cases showed chronic inflammation, (n=110, 42%). No cancer was identified in macroscopically non- suspicious looking foreskin. Clinically diagnosed balanitis, xerotica obliterans and suspicious looking foreskin was predictive of histological abnormality.

Conclusion: Sinister pathology was not identified in non-suspicious specimens. We recommend that foreskin of patients with a high risk for penile malignancy, and macroscopically abnormal looking foreskin should always be sent for histological analysis.

Keywords :

Circumcision; histopathology; abnormal; foreskin; cancer.

Full Article - PDF    Page 1-5

DOI : 10.9734/JAMPS/2017/38117

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