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Annual Research & Review in Biology

Annual Research & Review in Biology, ISSN: 2347-565X,Vol.: 16, Issue.: 5

 

Minireview-article

 

The Relationship between Homocysteine ​​and Fragility Fractures - A Systematic Review

 

 

Alexandru Filip1, Nina Filip2*, Bogdan Veliceasa1, Cristiana Filip2 and Ovidiu Alexa1

1Department of Orthopedics and Traumatology, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.

2Department of Biochemistry, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.

 

Abstracts

 

It is known that increased levels of homocysteine in plasma ​​have been associated with various diseases. Current studies show that homocysteine ​​is a new risk factor for the development of osteoporosis. Fragility fractures are associated with increased morbidity, mortality and cause substantial financial loss to the patients and their families.

This mini-review provides a critical overview of currently available studies, examining the relationship between plasma homocysteine levels and fragility fractures. In conclusion more studies are needed to establish a clear relationship between homocysteine and fractures in elderly patients.

 

Keywords :

Hyperhomocysteine; osteoporosis; fracture; methionine; bone fragility.

 

Full Article - PDF    Page 1-8    Article Metrics

 

DOI : 10.9734/ARRB/2017/36176

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