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Annual Research & Review in Biology

Annual Research & Review in Biology, ISSN: 2347-565X,Vol.: 16, Issue.: 5

Minireview-article

The Relationship between Homocysteine ​​and Fragility Fractures - A Systematic Review

 

Alexandru Filip1, Nina Filip2*, Bogdan Veliceasa1, Cristiana Filip2 and Ovidiu Alexa1

1Department of Orthopedics and Traumatology, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.

2Department of Biochemistry, University of Medicine and Pharmacy “Grigore T. Popa”, Iasi, Romania.

 

Article Information
Editor(s):
(1) George Perry, Dean and Professor of Biology, University of Texas at San Antonio, USA.
Reviewers:
(1) Kalima Nzanzu Adelard, Catholic University of Graben and Ruwenzori Official University, Democratic Republic of Congo.
(2) Ali Al Kaissi, Institute of Osteology, At the Hanusch Hospital of WGKK and AUVA Trauma Centre Meidling, Hanusch Hospital, Orthopaedic Hospital of Speising, Vienna, Austria.
(3) Patricia Canto, Universidad Nacional Autónoma de México, México.
Complete Peer review History: http://www.sciencedomain.org/review-history/20888

 

Abstracts

 

It is known that increased levels of homocysteine in plasma ​​have been associated with various diseases. Current studies show that homocysteine ​​is a new risk factor for the development of osteoporosis. Fragility fractures are associated with increased morbidity, mortality and cause substantial financial loss to the patients and their families.

This mini-review provides a critical overview of currently available studies, examining the relationship between plasma homocysteine levels and fragility fractures. In conclusion more studies are needed to establish a clear relationship between homocysteine and fractures in elderly patients.

 

Keywords :

Hyperhomocysteine; osteoporosis; fracture; methionine; bone fragility.

 

Full Article - PDF    Page 1-8    Article Metrics

 

DOI : 10.9734/ARRB/2017/36176

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