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Asian Journal of Chemical Sciences

Asian Journal of Chemical Sciences, 2456-7795,Vol.: 3, Issue.: 1


New Synthetic Pathways for Thiocarbohydrazide and Salicylaldehyde Azine Compounds


Solomon Omwoma Lugasi1*

1Department of Physical Sciences, Jaramogi Oginga Odinga University of Science and Technology, P.O.Box 210-40601, Bondo, Kenya.


Article Information
(1) Ho Soon Min, Department of Chemistry, INTI International University, Malaysia.
(2) Pradip K. Bhowmik, Department of Chemistry, University of Nevada Las Vegas, Maryland Parkway, USA.
(1) Joseph C. Sloop, Georgia Gwinnett College, USA.
(2) Pratima Parashar Pandey, IILM Institute for Higher Education, India.
(3) Leo Baldenegro, Center of Engineering and Industrial Development, Mexico.
Complete Peer review History: http://www.sciencedomain.org/review-history/20454




Thiocarbohydrazide synthesis is an important intermediate step for many hydrazine organic synthetic reactions. Synthesis of thiocarbohydrazide can be done by reaction of carbon disulfide with hydrazine (hydrazinolysis) in water at 0°C giving 25% yield (based on [hydrazine]). However, in this article, we achieve a 96% yield (based on [hydrazine]) by carrying out the reaction in methanol at 24°C. The thiocarbohydrazide is then used to synthesize 1,5-bis (2-hydroxybenzaldehyde) dithiocarbohydrazone. By refluxing the latter compound in pyridine at 80°C, it decomposes and rearranges to give salicylaldehyde azine.


Keywords :

Thiocarbohydrazide; salicylaldehyde azine; hydrazinolysis.


Full Article - PDF    Page 1-8    Article Metrics


DOI : 10.9734/AJOCS/2017/35504

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