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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 4, Issue.: 1 (01-10 January)

Original-research-article

Antigen Specific IgG4 in Patients with Gastrointestinal Complaints

 

Viktorija Priedite1,2*, Jevgenij Nikiforenko1, Natalja Kurjane2 and Juta Kroica2

1Laboratory Management and Consultancy, Riga, Latvia.
2Department of Biology and Microbiology, Riga Stradins University, Riga, Latvia.

Article Information

Editor(s):

(1) Salomone Di Saverio, Emergency Surgery Unit, Department of General and Transplant Surgery, S. Orsola Malpighi University Hospital, Bologna, Italy.

Reviewers:

(1) Anonymous.

(2) Anonymous.

Complete Peer review History: http://www.sciencedomain.org/review-history/2012

Abstracts

Aims: To find the antigen specific IgG4 in patients with gastrointestinal complaints and in control group, to demonstrate suitability of detection of IgG4 by using antigen panel.
Place and Duration of Study: Laboratory Management and Consultancy, Riga, Latvia, October 2012 - February 2013.
Methodology: The study included 147 patients (46 men, 101 women, aged from 1 to 76) with different complaints regarding gastrointestinal habitus. Antigen specific IgG4 analysis by using regional adopted antigen panel was executed.
Results: Almost all patients with gastrointestinal complaints -141 out of 147-have at least 2nd level antibodies, while in control group 15 out of 24 have 2nd level of antibodies.
Conclusion: IgG4 antigen specific antibody tests by panels could be used as a screening tool for food intolerance detection.

Keywords :

Antigen specific IgG4; food intolerance.

Full Article - PDF    Page 194-201 Article Metrics

DOI : 10.9734/BJMMR/2014/5696

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