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British Journal of Medicine and Medical Research

British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 21, Issue.: 11

Case Study

Spontaneous Regression of an Oral Manifestation of Plasmablastic Lymphoma: Literature Review and Commentary about the Phenomena


Natália Batista Daroit1, Viviane Palmeira da Silva1, Bruna Jalfim Maraschin1, Fernanda Visioli1, Pedro Bandeira Aleixo2, Márcia Gaiger de Oliveira1 and Pantelis Varvaki Rados1*

1Department of Conservative Dentistry, School of Dentistry, Universidade Federal do Rio Grande do Sul, Rua Ramiro Barcelos 2492/503, Porto Alegre, RS, 90035-003, Brazil.

2Department of Pathology, Universidade Federal de Ciências da Saúde de Porto Alegre, Rua Francisco Ferrer, 400 - Rio Branco, Porto Alegre - RS, 90420-140, Brazil.




Plasmablastic Lymphoma (PBL) is a hematolymphoid malignant disease that has a predilection for the oral cavity and jaw. The aim of this paper is report a total resolution of oral manifestation of PBL without any oncological treatment; this process is extremely rare and we discuss the mechanism which can occur. We present a case of PBL in left maxilla and oral mucosa in a woman HIV-positive patient. After an incisional biopsy an unusual outcome of spontaneous regression of the disease occurred, we reported the diagnostic process, the management and the follow up of case. We revised the similar cases reported in the literature and we will discuss the hypotheses how the phenomenon can occur. Although the PBLs are aggressive lesions, with questionable prognosis, the spontaneous regression can occur and the patient should be monitored for the risk of metastases and possible recurrence of the disease.


Keywords :

Acquired immunodeficiency syndrome; jaw cancer; maxilla; plasmablastic lymphoma; spontaneous neoplasm regression.


Full Article - PDF    Page 1-7    Article Metrics


DOI : 10.9734/BJMMR/2017/33683

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