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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 20, Issue.: 8

Case Report

A Rare Case Report of Duodenal Marginal Zone B-cell Lymphoma Related to Immunoproliferative Small Intestinal Disease and Associated Lymphoma (IPSID)


Ziad Aljarad1*, Mahmoud Nasser1, Ahmad Ghazal2, Mamdouh Alkhaled1, Batol Obeed3, M. Malek Shaghaleh4 and M. Wafa Hamoud Alhussein5

1Department of Gastroenterology, Aleppo University Hospital, Aleppo, Syria.

2Department of Surgery, Aleppo University Hospital, Aleppo, Syria.

3Department of Pathology, Aleppo University Hospital, Aleppo, Syria.

4Department of Internal Medicine, Aleppo University Hospital, Aleppo, Syria.

5Faculty of Medicine, University of Aleppo, Aleppo, Syria.

Article Information
(1) Chan-Min Liu, School of Life Science, Xuzhou Normal University, Xuzhou City, China.
(1) Huseyin Eken, Erzincan University,Turkey.
(2) Harmeet Singh, Aadhar Health Institute, India.
(3) Ahmed Gado, Misr International Hospital, Egypt.
Complete Peer review History: http://www.sciencedomain.org/review-history/18423


Marginal zone B-cell lymphoma is a unique lymphoma of the gastrointestinal tract most commonly in developing countries with poor socioeconomic conditions, poor hygiene, malnutrition, and a high degree of intestinal infections where IPSID is common.

We experienced a rare case of extranodal MZBCL in duodenum (sub type of MALT) in a 14-year-old girl who complained of epigastric pain.

Abdominal Computed Tomography (CT) with Intravenous (IV) contrast showed mixed mass infiltrate the intestinal wall with mesenteric lymphadenopathy.

Upper gastrointestinal tract endoscopy had showed obstruction in the 2nd segment of duodenum, biopsies were taken.

Pathology report according to findings refers to immunoproliferative small intestinal disease and associated lymphoma (IPSID) and by immunostains, cells features are compatible with extranodal marginal zone B cell lymphoma which is sub type of MALT lymphoma.

Keywords :

Duodenum; IPSID; marginal zone B-cell lymphoma; gastrointestinal tract lymphoma.

Full Article - PDF    Page 1-4

DOI : 10.9734/BJMMR/2017/32496

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