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Journal of Advances in Medical and Pharmaceutical Sciences, 2394-1111,Vol.: 11, Issue.: 3

Original-research-article

Antibiotics Susceptibility Profile and Prevalence of Gram-negative Uropathogens from Asymptomatic Bacteriuria among Female Students in a University in Northern Nigeria

 

P. A. Ezeh1*, J. C. Igwe2, R. O. Bolaji1 and B. O. Olayinka1

1Department of Pharmaceutics and Pharmaceutical Microbiology, Ahmadu Bello University, Zaria, Nigeria.

2Department of Medical Biotechnology, National Biotechnology Development Agency, Abuja, Nigeria.

Article Information
Editor(s):
(1) Hamdy A. Sliem, Internal Medicine, Suez Canal University, Egypt.
Reviewers:
(1) Maria Demetriou, Democritus University of Thrace, Greece.
(2) Akobi Oliver Adeyemi, Federal Medical Centre, Nigeria.
Complete Peer review History: http://www.sciencedomain.org/review-history/17437

Abstracts

Asymptomatic bacteriuria among healthy female students is a common occurrence that is frequently ignored and this is attributed to the fact that Pre-menopausal, non-pregnant women with asymptomatic bacteriuria experience no adverse effects and usually will clear their bacteriuria spontaneously. However, these women are more likely to experience subsequent symptomatic UTI than women who do not have asymptomatic bacteriuria. The aim of this study is to determine the incidence of asymptomatic bacteriuria among female students of Ahmadu Bello University (A.B.U), Zaria Main Campus.

Methodology: A total of 400 midstream clean-catch urine samples were analyzed using standard microbiological methods. Organisms were isolated from positive urine samples and the isolates were identified using MicrogenTM GNA-ID kit. Antibiotic susceptibility was carried out on the isolates using the modified Kirby-Bauer disc diffusion test method.

Results: Bacteriological analysis of the urine samples revealed a 16% (63/400) asymptomatic bacteriuria among female students in A.B.U main campus with a total of 148 bacteria isolates. The most prevalent bacteria were Klebsiella species and Acinetobacter species (19.59%), followed by Enterobacter species (17.57%) and Escherichia species (11.49%). A high incidence of resistance to Tetracycline (74%) and Cephalosporin (78%) was observed (Fig. 2).

Conclusion: This study showed that there is an incidence of asymptomatic bacteriuria 16% (63) among healthy female students in A.B.U main campus and these isolates show a high resistance to Tetracycline (74%) and Cephalosporin (78%) antibiotics.

Keywords :

Urine; asymptomatic bacteriuria; uropathogens; antibiotics resistance.

Full Article - PDF    Page 1-9 Article Metrics

DOI : 10.9734/JAMPS/2016/27929

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