Journal of Complementary and Alternative Medical Research, ISSN: 2456-6276,Vol.: 2, Issue.: 1
Effect of Ethanol Leaves Extract of Anthocleista vogelii and Cocos nucifera Water on Some Haematological Indices in Wistar Rats
Moke Emuesiri Goodies1* 1Department of Pharmacology and Therapeutics, Delta State University, Abraka, Delta State, Nigeria.
Moke Emuesiri Goodies1*
1Department of Pharmacology and Therapeutics, Delta State University, Abraka, Delta State, Nigeria.
(1) Ahmed Moussa, Pharmacognosy and Api-Phytotherapy Research Laboratory, Mostaganem University, Algeria.
(1) Oluwakanyinsola Adeola Salawu, National Institute for Pharmaceutical Research & Development, Nigeria.
(2) Remya Mohanraj, MGM Medical College, India.
Complete Peer review History: http://www.sciencedomain.org/review-history/17369
Aim: To evaluate the effect of ethanol leaves extract of Anthocleista vogelii and Cocos nucifera water on haematological parameters in wistar rats.
Study Design: Haematology.
Place and Duration of Study: Department of Pharmacology and Therapeutics, Delta State University, Abraka Delta State, Nigeria, between July and August, 2015.
Methodology: Thirty rats divided into six groups of five were used for the study. Doses of 10 ml/kg of Cocos nucifera, 200 mg/kg, and 400 mg/kg of Anthocleista vogelii, and 200 mg/kg and 400 mg/kg of Anthocleista vogelii combination with Cocos nucifera (1:1) were administered to the animals, while the control group received normal saline (10 ml/kg). The experimental animals were administered the extracts orally once daily for 2 weeks according to their body weights, after which blood samples were obtained for haematological analysis.
Results: Anthocleista vogelii and Cocos nucifera extracts showed significant (P<0.05) increase in RBC, WBC, and PCV values.
Conclusion: The ethanol leaves extract of Anthocleista vogelii and its combination with Cocos nucifera water has positive haematopoietic effects.
Anthocleista vogelii; Cocos nucifera; haematological parameters; anaemia.
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