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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 18, Issue.: 3

Case Study

Maxillary Clear Cell Odontogenic Carcinoma - A Rare Entity


T. L. Yogesh1, Hema Keswani1*, Akshay Shetty2 and Hemavathy S1

1Department of Oral and Maxillofacial Pathology, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Cholanagar, Hebbal, Bangalore-560032, Karnataka, India.

2Department of Oral and Maxillofacial Surgery, Sri Rajiv Gandhi College of Dental Sciences and Hospital, Bangalore-560032, Karnataka, India.

Article Information
(1) James Anthony Giglio, Adjunct Clinical Professor of Oral and Maxillofacial Surgery, School of Dentistry, Virginia Commonwealth University, Virginia, USA.
(1) Maya Ramesh, Vinayaka Missions Sankarachariyar Dental Colege, Vinayaka University, India.
(2) Shoko Gamoh, Osaka Dental University, Japan.
Complete Peer review History: http://www.sciencedomain.org/review-history/16517


Clear cell odontogenic carcinoma (CCOC) is a rare odontogenic tumor with predominance in the posterior mandible, usually occurring in the fifth to seventh decades of life, and being found more commonly in females. It is a potentially aggressive tumour, capable of recurring frequently, locally invasive, and with distant metastases. Here we report a case of clear cell odontogenic carcinoma of maxilla in a 70 years old female, with a tumor mass on right side of the palate in the premolar - molar region. Microscopically, biphasic population of cells with characteristic polygonal, clear cells, hyperchromatic and basaloid cells with eosinophillic cytoplasm were seen. There was positive immunoreactivity with markers Ki67 and cytokeratin CK19. The significance of histochemical and immunohistochemical resources in the correct diagnosis of CCOC is presented.

Keywords :

Clear cell odontogenic carcinoma; clear cell; maxilla.

Full Article - PDF    Page 1-5

DOI : 10.9734/BJMMR/2016/27190

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