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British Journal of Medicine and Medical Research, ISSN: 2231-0614,Vol.: 14, Issue.: 4

Original-research-article

Frequency Distribution of Hemoglobin Variants among Teenagers

 

A. A. Adeyemi1*, A. O. Ladipo2, O. A. Omolade3 and D. D. Ogbaro1

1Department of Hematology, Babcock University, Ilisan-Remo, Ogun-State, Nigeria.

2Department of Chemical Pathology, Babcock University Teaching Hospital, Ilisan-Remo, Ogun-State, Nigeria.

3Department of Community Medicine and Primary Care, Olabisi Onabanjo University, Sagamu, Ogun-State, Nigeria.

Article Information
Editor(s):
(1) Alex Xiucheng Fan, Department of Biochemistry and Molecular Biology, University of Florida, USA.
Reviewers:
(1) Sandrine Comparsi Wagner, Federal University of Health Sciences of Porto Alegre, Brazil.
(2) Anonymous, Universidade Federal de Minas Gerais, Brazil.
(3) Mamta Soni, Apollo Hospitals, Chennai, India.
(4) Marco Matteo Ciccone, University of Bari, Italy.
Complete Peer review History: http://sciencedomain.org/review-history/13596

Abstracts

Aim: The intent of this study is to report the distribution of hemoglobin variants among teenagers in South -West Nigeria.

Study Design: Cross sectional study.

Place/Duration: Babcock University, Ilisan-Remo, Ogun State, South-West Nigeria between September 2013 and March 2015.

Methods: Hemoglobin (Hb) variants were determined in two thousand, four hundred and six teenagers using the alkaline electrophoresis method.

Results: The distribution of Hemoglobin electrophoresis is as follows; HbAA 1821 (75.7%), HbAS 498 (20.7%), HbAC 47 (2.0%), HbCC 01 (0.0%), HbSC 12 (0.5%), HbSS 27 (1.1%).

Conclusion: The incidence of hemoglobinopathies is reduced among the teenagers in South- West Nigeria.

Keywords :

Incidence; hemoglobinopathies; sickle cell trait; Nigeria; sickle cell disease; teenagers.

Full Article - PDF    Page 1-5

DOI : 10.9734/BJMMR/2016/23426

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