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Journal of Advances in Biology & Biotechnology, 2394-1081,Vol.: 5, Issue.: 4


Implication of Testosterone in Human Puberty Attainment


Olufemi Ebenezer Akinluwade1,2, Alphonsus Ekpe Udoh1,2 and Kunle Joseph  Akinluwade3,4,5*

1Department of Chemical Pathology, University of Calabar Teaching Hospital (UCTH), Calabar 540213, Nigeria.

2Department of Medical Laboratory Science, Chemical Pathology Unit, University of Calabar, 540213, Nigeria.

3Department of Chemical, Materials and Biomolecular Engineering, University of Connecticut/University of Connecticut Health Center (UCHC), Farmington, CT 06032, USA.

4Department of Materials Science and Engineering, Obafemi Awolowo University (OAU), Ile-Ife, 220282, Nigeria.

5Department of Research and Development, Prototype Engineering Development Institute, [National Agency for Science and Engineering Infrastructure, NASENI], Ilesa, 233036, Nigeria.

Article Information
(1) Anil Kumar, School of Biotechnology, Devi Ahilya University, Madhya Pradesh, India.
(2) Reviewers:
(1) Abrao Rapoport, Sao Paulo University, Brazil.
(2) Antonina Yashchenko, Danylo Halytsky Lviv National Medical University, Ukraine.
(3) Anonymous, Erzincan University, Turkey.
(4) Sema Kalkan Ucar, Ege University, Turkey.
Complete Peer review History: http://sciencedomain.org/review-history/13225


This study evaluated and compared the serum levels of testosterone in male and female subjects aged 6—10 years. It also assessed the number of children among the subjects who could be potential candidates for precocious puberty based on their hormone levels. Male subjects in the study were 78 (44.1%) with a mean age of 8.3±1.4 years, height of 1.31±0.08 m, mean weight of 26.20±4.83 Kg, and Body Mass Index (BMI) of 15.30±1.71 kg/m2. Female subjects were 99 (55.9%) with a mean age of 8.55±1.37 years, height of 1.34±0.10 m, weight of 27.78±5.36 Kg, and BMI of 15.38±1.68 kg/m2. Results from statistical and clinical analyses showed that female subjects were significantly heavier and taller than male subjects (p <0.05) but the BMIs for both sexes were identical (p>0.05). Male subjects had mean testosterone of 0.49±0.38 ng/ml compared with mean testosterone of 0.57±0.59 for the female subjects. There is no significant age dependent differences in the levels of testosterone in both sexes. Based on the levels of testosterone of the children, only one of the children was adjudged qualified as candidate for precocious puberty.

Keywords :

Testosterone; precocious puberty; children; age; hormone; BMI; blood.

Full Article - PDF    Page 1-6

DOI : 10.9734/JABB/2016/22543

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